HuagongsheHuagongshe Chemistry Print Report · For research reference only
furo[2,3-c]pyridazin-5(6H)-one O-methyl oxime → 4-methoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one O-methyl oxime
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | furo[2,3-c]pyridazin-5(6H)-one O-methyl oxime | HCID 86721901 | — |
| Reactant | 4-methoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one | HCID 86721942 | — |
| Product | 4-methoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one O-methyl oxime | HCID 86721943 | — |
Reaction Steps
This compound was prepared using a method analogous to that of furo[2,3-c]pyridazin-5(6H)-one O-methyl oxime (A.2.3.3), 4-methoxy-6-methylfuro[2,3-b]pyridin-3(2H)-one replacing furo[2,3-c]pyridazin-5(6H)-one. Purification by (KP-SIL™ from Biotage) using Hept/EtOAc (1/1) gives the desired product as white solid;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221832B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-cd75c07d747a434399423afe680fb80d |
| Source note | uspto-grants-2015_12 |