Acetone → HCID 56989771, compound

HRID 1508659Notes

Reaction equation

HRID 1508659 reaction equation
Cl.[Cl:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH2:4][CH2:5][CH:6]=NOC.C=O.CC(C)=[O:20]>O.CCCCCC>[Cl:2][CH:3]([C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)[CH2:4][CH2:5][CH:6]=[O:20]

Participants

7

Reactant 4

HCID 180AcetoneHCID 313Hydrochloric AcidHCID 712FormaldehydeHCID 118108953HCID 118108953, compound

Product 1

HCID 56989771HCID 56989771, compound

Reagents, catalysts & solvents 2

HCID 962WaterSolventHCID 8058HexaneSolvent

Procedure

0.1 mL of 2 mol/L hydrochloric acid was added to a mixture of 82 mg of (4-chloro-4-phenylbutylidene)(methoxy)amine, 0.32 mL of a 36% formalin aqueous solution and 4 mL of acetone, and the obtained mixture was then stirred at room temperature for 0.5 hours. Thereafter, hexane and water were added to the reaction mixture, and the water layer was then removed. The solvent was distilled away under reduced pressure, so as to obtain 61 mg of 4-chloro-4-phenylbutanal in the form of a colorless oily product.

Workup

  1. customthe water layer was then removed
  2. distillationThe solvent was distilled away under reduced pressure

Sources & evidence

ORD record
ord-9b29919f0fea4664a96e5a06c5e000ab
Source dataset
uspto-grants-2015_12
Patent number
US09221865B2

Reaction notes

Loading…