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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1509212Generated: October 31, 2026

Potassium Carbonate → HCID 123866562, compound

https://huagongshe.com/reaction/1509212

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantBromoacetonitrileHCID 11534—
ReactantHCID 67257090HCID 67257090—
SolventDimethylformamideHCID 6228—
ProductHCID 123866562HCID 123866562—

Reaction Steps

A solution of tert-butyl 1-(4-(3-(2-hydroxyethyl)-2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutylcarbamate (51 mg, 0.099 mmol) in DMF(2 ml) was added potassium carbonate (41 mg) and 2-bromoacetonitrile (35.5 mg, 0.297 mmol). The reaction mixture was stirred at 50 degree for 3 h.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09221838B2
Source datasetuspto-grants-2015_12
ORD IDord-07d955e3100444f4b809e09d95c0dd9c
Source noteuspto-grants-2015_12