HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 123866562, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Bromoacetonitrile | HCID 11534 | — |
| Reactant | HCID 67257090 | HCID 67257090 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 123866562 | HCID 123866562 | — |
Reaction Steps
A solution of tert-butyl 1-(4-(3-(2-hydroxyethyl)-2-oxo-7-phenyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]oxazin-6-yl)phenyl)cyclobutylcarbamate (51 mg, 0.099 mmol) in DMF(2 ml) was added potassium carbonate (41 mg) and 2-bromoacetonitrile (35.5 mg, 0.297 mmol). The reaction mixture was stirred at 50 degree for 3 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09221838B2 |
| Source dataset | uspto-grants-2015_12 |
| ORD ID | ord-07d955e3100444f4b809e09d95c0dd9c |
| Source note | uspto-grants-2015_12 |