反应详情

Ethyl-3,3,3-trifluoropropanoate (2.5 g, 0.016 mol) and hydrazine monohydrate (1.2 g, 0.024 mol) were heated to reflux for 1 hour. The reaction mixture was concentrated under reduced pressure and the residue was treated with toluene (100 ml×3) to azeotrope hydrazine in excess.

1. temperatureto reflux for 1 hour
2. concentrationThe reaction mixture was concentrated under reduced pressure
3. additionthe residue was treated with toluene (100 ml×3)