Hydrochloric Acid → 2-(1-(4-Bromophenyl)-3-oxocyclobutyl)isoindoline-1,3-dione

Participants

Reaction Conditions

Reaction Steps

A solution of 2-(1-(4-bromophenyl)-3,3-dimethoxycyclobutyl)isoindoline-1,3-dione (0.3 g, 0.72 mmol) in Acetone (30 ml) was added 6M HCl (3 ml) and the resulting solution was stirred at 50° C. for 2 h. The reaction mixture was concentrated to give product 0.26 g.).

Provenance & Evidence