Diethyl Ether → HCID 86720796, compound

HRID 1509368Notes

Reaction equation

HRID 1509368 reaction equation
[C:1](Cl)(=[O:10])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.C([O:14]CC)C.[CH2:17]1C[O:20][CH2:19][CH2:18]1>>[C:1]([O-:10])(=[O:14])[CH:2]=[CH:3][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH2:19]([O:20][C:1](=[O:10])[CH:2]=[CH2:3])[CH2:18][CH3:17]

Participants

4

Reactant 3

HCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 660233-Phenylprop-2-enoyl chloride

Product 1

HCID 86720796HCID 86720796, compound

Procedure

The cinnamoyl chloride (5 g, 33.7 mmol), 3-hydroxy propyl acrylate (35.0 mmol), and TEA (105 mmol) were dissolved in THF and stirred at the room temperature for 24 hours. After completion of the stirring, diethylether was added to form a precipitate, which was then filtered out. A column chromatography using a developing solvent (EA:hexane=1:4) was carried out to yield a titled product, cinnamate-propyl-acrylate.

Workup

  1. customto form a precipitate, which
  2. filtrationwas then filtered out

Sources & evidence

ORD record
ord-816d58d9f30b4a0faa731818007504f8
Source dataset
uspto-grants-2015_12
Patent number
US09223177B2

Reaction notes

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