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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1509816Generated: October 30, 2026

5-Aminosalicylic Acid → HCID 9856513, compound

https://huagongshe.com/reaction/1509816

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Aminosalicylic AcidHCID 4075—
Reactant4-Fluorobenzyl bromideHCID 68021—
ProductHCID 9856513HCID 985651356.4%

Reaction Steps

By following the similar procedure in Synthesis Example 1 by using 5-aminosalicylic acid (500 mg, 3.26 mmole) and 4-fluorobenzyl bromide (740 mg, 3.92 mmole), 480 mg (44% yield) of 5-(4-fluorobenzyl)aminosalicylic acid was obtained as a white solid.:mp>210° C. (decompose).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08211877B2
Source datasetuspto-grants-2012_07
ORD IDord-507ab35cf91a44c6a2cb0a9784f3d658
Source noteuspto-grants-2012_07