HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-6,7-dimethoxyquinoline → 6-(6,7-Dimethoxyquinolin-4-yloxy)-1-naphthoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-6,7-dimethoxyquinoline | HCID 459610 | — |
| Reactant | 6-Hydroxy-1-naphthoic acid | HCID 5463800 | — |
| Product | 6-(6,7-Dimethoxyquinolin-4-yloxy)-1-naphthoic acid | HCID 24822603 | 68.4% |
Reaction Steps
The title compound (1.95 g, 68% yield) was prepared as a brown solid from 6-hydroxy-1-naphthoic acid (1.43 g, 7.6 mmol) and 4-chloro-6,7-dimethoxyquinoline (2.04 g, 9.14 mmol) by an analogous procedure to that described in example 1. LC-MS (m/z) 376 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08211901B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-d42c6c205d244f9f9e94ca22d7c428e0 |
| Source note | uspto-grants-2012_07 |