O-Phenylenediamine → HCID 59590547, compound

HRID 1509997Notes

Reaction equation

HRID 1509997 reaction equation
[C:1]([C:3]1[CH:11]=[CH:10][C:6]([C:7]([OH:9])=O)=[CH:5][N:4]=1)#[N:2].[C:12]1([NH2:19])[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[NH2:18]>>[NH2:2][CH2:1][C:3]1[CH:11]=[CH:10][C:6]([C:7]([NH:18][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[NH2:19])=[O:9])=[CH:5][N:4]=1

Participants

3

Reactant 2

HCID 7243O-PhenylenediamineHCID 27611086-Cyanopyridine-3-carboxylic acid

Product 1

HCID 59590547HCID 59590547, compoundYield 65%

Procedure

The title compound (157 mg, 65% yield) was prepared as a grey solid from 6-cyano-nicotinic acid (296 mg, 2 mmol) and o-phenylenediamine (864 mg, 8 mmol) by an analogous procedure to that described in example 8. LC-MS (m/z) 243 (M+1).

Sources & evidence

ORD record
ord-145fcb2328d546d28011e7cef47d068e
Source dataset
uspto-grants-2012_07
Patent number
US08211901B2

Reaction notes

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