Hydrochloric Acid → HCID 68497344, compound

HRID 1510028Notes

Reaction equation

HRID 1510028 reaction equation
[CH2:1]([C@@:3]12[CH2:15][C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C@@H:4]1[NH:5][CH2:6][CH2:7][CH2:8]2)[CH3:2].[ClH:16]>>[ClH:16].[CH2:1]([C@@:3]12[CH2:15][C:14]3[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=3)[C@@H:4]1[NH:5][CH2:6][CH2:7][CH2:8]2)[CH3:2]

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 42633848HCID 42633848, compound2×

Product 1

HCID 68497344HCID 68497344, compound

Procedure

(−)-(4aR*,9bR*)-4a-Ethyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine and (+)-(4aR*,9bR*)-4a-ethyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine were each made into a hydrochloride by a conventional method, washed with ethyl acetate, and then collected by filtration to obtain (4aR*,9bR*)-4a-ethyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine hydrochloride and an enantiomer thereof, respectively, as a colorless powder.

Workup

  1. washwashed with ethyl acetate
  2. filtrationcollected by filtration

Sources & evidence

ORD record
ord-d3d75a09580f499dbccc4a73641f17b8
Source dataset
uspto-grants-2012_07
Patent number
US08211907B2

Reaction notes

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