Hydrochloric Acid → HCID 68497645, compound

HRID 1510029Notes

Reaction equation

HRID 1510029 reaction equation
[CH3:1][C@@:2]12[CH2:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C@:3]1([CH3:15])[NH:4][CH2:5][CH2:6][CH2:7]2.[ClH:16]>>[ClH:16].[CH3:1][C@@:2]12[CH2:14][C:13]3[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=3)[C@:3]1([CH3:15])[NH:4][CH2:5][CH2:6][CH2:7]2

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 42633851HCID 42633851, compound2×

Product 1

HCID 68497645HCID 68497645, compound

Procedure

(−)-(4aR*,9bR*)-4a,9b-Dimethyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine and (+)-(4aR*,9bR*)-4a,9b-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine were each made into a hydrochloride by a conventional method, washed with ethyl acetate, and then collected by filtration to obtain (4aR*,9bR*)-4a,9b-dimethyl-2,3,4,4a,5,9b-hexahydro-1H-indeno[1,2-b]pyridine hydrochloride and an enantiomer thereof, respectively, as a colorless powder.

Workup

  1. washwashed with ethyl acetate
  2. filtrationcollected by filtration

Sources & evidence

ORD record
ord-09b727cd9fe646e0ac647f229b7b13a6
Source dataset
uspto-grants-2012_07
Patent number
US08211907B2

Reaction notes

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