O-Cresol → HCID 66920488, compound

HRID 1510068Notes

Reaction equation

HRID 1510068 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:24]3[C:19](=[CH:20][C:21]([Cl:25])=[CH:22][CH:23]=3)[N:18]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:17]=2Cl)=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[CH3:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][C:35]=1[OH:40]>>[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][N:11]([C:14]([C:16]2[C:24]3[C:19](=[CH:20][C:21]([Cl:25])=[CH:22][CH:23]=3)[N:18]([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:17]=2[O:40][C:35]2[CH:36]=[CH:37][CH:38]=[CH:39][C:34]=2[CH3:33])=[O:15])[CH2:10][CH2:9]1)=[O:7])([CH3:3])([CH3:4])[CH3:2]

Participants

3

Reactant 2

HCID 335O-CresolHCID 66920483HCID 66920483, compound

Product 1

HCID 66920488HCID 66920488, compound

Procedure

From the compound of step 4 (100 mg, 211 μmol), the title compound was prepared analogously as described in example 1, step 2, using 2-methylphenol. Yield: 29 mg.

Sources & evidence

ORD record
ord-a5eaaf417913455f9e2730949dc3e8d0
Source dataset
uspto-grants-2012_07
Patent number
US08211885B2

Reaction notes

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