Hydrazine → HCID 68081121, compound

Participants

Reaction Steps

To a solution of cis 2-[2-(3-methoxyphenyl)cyclopentyl]-1H-isoindole-1,3(2H)-dione (0.23 g, 0.72 mmol) in toluene (3 mL) was added hydrazine (0.23 mL, 7.23 mmol). After stirring at room temperature for 1 h, then 95° C. for 4 h, a precipitate formed. The mixture was cooled to rt, filtered, and washed with toluene. The filtrate was concentrated to give the desired product, which was used without further purification.

Provenance & Evidence