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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1510317Generated: November 3, 2026

3,5-dichloro-N-(1-methyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-phenylsulphonamide → 5-Amino-1-methyl-2-oxoindoline

https://huagongshe.com/reaction/1510317

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,5-dichloro-N-(1-methyl-2-oxo-2,3-dihydro-1H-indol-5-yl)-phenylsulphonamideHCID 59446533—
SolventMethanolHCID 887—
Product5-Amino-1-methyl-2-oxoindolineHCID 22692470—

Reaction Steps

The reaction is carried out in methanol. The crude product is further reacted directly in V (5).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08211923B2
Source datasetuspto-grants-2012_07
ORD IDord-188f16347e2d4126b658ee9cf10e8665
Source noteuspto-grants-2012_07