Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 15104Generated: October 26, 2026

Trifluoroacetic acid → (R)-2-[(5-chloro-thiophene-2-carbonyl)-amino]-propionic acid

https://huagongshe.com/reaction/15104

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
Reactanttert.-butyl(R)-2-[(5-chloro-thiophene-2-carbonyl)-amino]-propionateHCID 68637194—
SolventDichloromethaneHCID 6344—
Product(R)-2-[(5-chloro-thiophene-2-carbonyl)-amino]-propionic acidHCID 68637698—

Reaction Steps

Prepared analogously to Example 2e from tert.-butyl(R)-2-[(5-chloro-thiophene-2-carbonyl)-amino]-propionate with TFA in dichloromethane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07732466B2
Source datasetuspto-grants-2010_06
ORD IDord-5eda29662cb946f2bc1e4c611605929e
Source noteuspto-grants-2010_06