Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Ceftiofur Hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Sodium Chloride | HCID 5234 | — |
| 반응물 | Diisopropyl Ether | HCID 7914 | — |
| 반응물 | Ceftiofur Sodium | HCID 23671563 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | Ceftiofur Hydrochloride | HCID 9937686 | — |
반응 단계
To a suspension of crystalline Ceftiofur sodium (10 g) in water (30 ml) was added THF (87 ml) at 10-30° C. To that sodium chloride (14 g) was added. pH of the solution was adjusted to 2.5-3.5. Organic layer pH was adjusted to 0.5-1.5 using conc. HCl. Addition of diisopropyl ether followed by filtration yielded pure title compound.]
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08212024B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-d0d23c507255493f9027168858d1b6d2 |
| 출처 메모 | uspto-grants-2012_07 |