HCID 86644151, compound → 2-Ethylpyridin-3-yl acetate

HRID 1511097Notes

Reaction equation

HRID 1511097 reaction equation
[C:1]([O:4][C:5]1[C:6]([C:11]#[CH:12])=[N:7][CH:8]=[CH:9][CH:10]=1)(=[O:3])[CH3:2]>C(O)C.O=[Pt]=O>[C:1]([O:4][C:5]1[C:6]([CH2:11][CH3:12])=[N:7][CH:8]=[CH:9][CH:10]=1)(=[O:3])[CH3:2]

Participants

4

Reactant 1

HCID 86644151HCID 86644151, compound

Product 1

HCID 671213462-Ethylpyridin-3-yl acetateYield 100%

Reagents, catalysts & solvents 2

HCID 345198Adams' catalystCatalystHCID 702EthanolSolvent

Procedure

To a solution of 2-ethynylpyridin-3-yl acetate (5.0 g, 31 mmol) in ethanol (50 mL) was added PtO2 (0.50 g, 2.2 mmol). The mixture was degassed with nitrogen and placed under a double-layer balloon of hydrogen. The reaction was stirred at ambient temperature for 30 minutes. The mixture was filtered and concentrated in vacuo to give 2-ethylpyridin-3-yl acetate (5.1 g, 31 mmol) that was used without further purification.

Workup

  1. customThe mixture was degassed with nitrogen
  2. filtrationThe mixture was filtered
  3. concentrationconcentrated in vacuo

Sources & evidence

ORD record
ord-8cef54ad2ac24185b498ed074f201a19
Source dataset
uspto-grants-2012_07
Patent number
US08212045B2

Reaction notes

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