反应详情

Cocrystals of fluoxetine HCl:benzoic acid were formed using the following procedures. In one preparation, a 505 mg sample of fluoxetine HCl and 178 mg of benzoic acid were dissolved with heating in 5 mL of acetonitrile. The solution was allowed to crystallize in a small crystallization dish. Well-formed crystalline material formed within 7 minutes. This material was isolated on filter paper and dried in the air to yield 546 (80%) of fluoxetine HCl:benzoic acid (1:1) cocrystal.

1. customIn one preparation
2. customto crystallize in a small crystallization dish
3. customWell-formed crystalline material formed within 7 minutes
4. customThis material was isolated
5. filtrationon filter paper
6. customdried in the air