1,2-Dichloro-4-fluorobenzene → 7-(3,4-Dichlorophenyloxy)-5-(2-fluoroethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrochloride

Participants

Reaction Steps

The same method as in Reference Example 3 was conducted using 5-(2-fluoroethyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol (Reference Example 17) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3,4-dichloro-1-fluorobenzene instead of 1,3-difluorobenzene to give the objective compound.

Provenance & Evidence