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HRID 1511688作成日:2026年10月26日

Benzene, 1,2-dichloro-3-fluoro- → 8-(2,3-Dichlorophenyloxy)-5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepine

https://huagongshe.com/reaction/1511688

反応式

関与物質

役割名称HCID仕込み量
反応物Benzene, 1,2-dichloro-3-fluoro-HCID 119011—
反応物5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepin-8-olHCID 68409910—
生成物8-(2,3-Dichlorophenyloxy)-5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepineHCID 25027799—

反応手順

The same method as in Example 1 was conducted using 5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepin-8-ol (Reference Example 21) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 2,3-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US08217031B2
出典データセットuspto-grants-2012_07
ORD IDord-3178b58cb8fc4e2297f6e85dfa476c43
出典メモuspto-grants-2012_07