D-Tartaric acid → HCID 68410027, compound

HRID 1511711Notes

Reaction equation

HRID 1511711 reaction equation
[CH3:1][C:2]1[O:23][C:5]2[CH2:6][N:7]([CH3:22])[CH2:8][CH2:9][CH:10]([O:11][C:12]3[C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=[CH:14][CH:13]=3)[C:4]=2[CH:3]=1.[C:24]([OH:33])(=[O:32])[C@H:25]([C@@H:27]([C:29]([OH:31])=[O:30])[OH:28])[OH:26]>CO>[C:29]([C@H:27]([C@@H:25]([C:24]([OH:33])=[O:32])[OH:26])[OH:28])([OH:31])=[O:30].[CH3:1][C:2]1[O:23][C:5]2[CH2:6][N:7]([CH3:22])[CH2:8][CH2:9][CH:10]([O:11][C:12]3[C:21]4[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=4)[CH:15]=[CH:14][CH:13]=3)[C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 439655D-Tartaric acidHCID 25027581HCID 25027581, compound

Product 1

HCID 68410027HCID 68410027, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The free body of 2,7-dimethyl-4-(naphthalen-1-yloxy)-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine provided with Example 140 was dissolved in methanol, and then into the resulting methanol solution was added 1 equivalent of D-tartaric acid and was stirred for 1 hour. The mixture was concentrated to give the objective compound.

Workup

  1. concentrationThe mixture was concentrated
  2. customto give the objective compound

Sources & evidence

ORD record
ord-c1f5fed132d841f5b44a65e5fb5cdba5
Source dataset
uspto-grants-2012_07
Patent number
US08217031B2

Reaction notes

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