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Citric Acid → 8-(3,4-Dichlorophenyloxy)-5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepine citrate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Citric Acid | HCID 311 | — |
| 反応物 | 8-(3,4-Dichlorophenyloxy)-5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepine | HCID 68409336 | — |
| 溶媒 | Methanol | HCID 887 | — |
| 生成物 | 8-(3,4-Dichlorophenyloxy)-5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepine citrate | HCID 68409335 | — |
反応手順
The free body of 8-(3,4-dichlorophenyloxy)-5-methyl-5,6,7,8-tetrahydro-4H-furo[3,2-c]azepine provided with Example 158 was dissolved in methanol, and then into the resulting methanol solution was added 1 equivalent of citric acid and was stirred for 1 hour. The mixture was concentrated to give the objective compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US08217031B2 |
| 出典データセット | uspto-grants-2012_07 |
| ORD ID | ord-0419533ca59045f690a0f301972099d9 |
| 出典メモ | uspto-grants-2012_07 |