Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Bromo-2,5-dichloro-3-fluorobenzene → 4-(3-Bromo-2,5-dichlorophenyloxy)-2-methyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Bromo-2,5-dichloro-3-fluorobenzene | HCID 618513 | — |
| 반응물 | 2-methyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol | HCID 68410069 | — |
| 생성물 | 4-(3-Bromo-2,5-dichlorophenyloxy)-2-methyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepine hydrochloride | HCID 68410546 | — |
반응 단계
The same method as in Example 3 was conducted using 2-methyl-5,6,7,8-tetrahydro-4H-furo[2,3-c]azepin-4-ol (Reference Example 44) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3-bromo-2,5-dichloro-1-fluorobenzene instead of 1,3-difluorobenzene to give the objective compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08217031B2 |
| 출처 데이터셋 | uspto-grants-2012_07 |
| ORD ID | ord-31a554e0c7b34b5690d656152ecd6edc |
| 출처 메모 | uspto-grants-2012_07 |