HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Cyano-4-fluoronaphthalene → 7-(4-Cyanonaphthalen-1-yloxy)-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Cyano-4-fluoronaphthalene | HCID 2736734 | — |
| Reactant | 2-Methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol | HCID 68410459 | — |
| Product | 7-(4-Cyanonaphthalen-1-yloxy)-2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridine | HCID 68411180 | — |
Reaction Steps
The same method as in Example 1 was conducted using 2-methyl-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-7-ol (Reference Example 30) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 4-cyano-1-fluoronaphthalene instead of 1-fluoronaphthalene to give the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217031B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-40d4a5734349471b87383da0c9b430ad |
| Source note | uspto-grants-2012_07 |