HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,2-Dichloro-4-fluorobenzene → 4-(3,4-Dichlorophenyloxy)-2,7-dimethyl-5,6,7,8-tetrahydro-4H-thieno[2,3-c]azepine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,2-Dichloro-4-fluorobenzene | HCID 74028 | — |
| Edukt | 2,7-dimethyl-5,6,7,8-tetrahydro-4H-thieno[2,3-c]azepin-4-ol | HCID 68409884 | — |
| Produkt | 4-(3,4-Dichlorophenyloxy)-2,7-dimethyl-5,6,7,8-tetrahydro-4H-thieno[2,3-c]azepine | HCID 68410915 | — |
Reaktionsschritte
The same method as in Example 1 was conducted using 2,7-dimethyl-5,6,7,8-tetrahydro-4H-thieno[2,3-c]azepin-4-ol (Reference Example 23) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3,4-dichloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08217031B2 |
| Quelldatensatz | uspto-grants-2012_07 |
| ORD ID | ord-e27270e06c694dfe862a3c0b229078ee |
| Quellennotiz | uspto-grants-2012_07 |