HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Bromo-2-chloro-3-fluorobenzene → 7-(3-Bromo-2-chlorophenyloxy)-4,5,6,7-tetrahydrofuro[3,2-c]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Bromo-2-chloro-3-fluorobenzene | HCID 3739301 | — |
| Reactant | 4,5,6,7-Tetrahydrofuro[3,2-c]pyridin-7-ol | HCID 55300159 | — |
| Product | 7-(3-Bromo-2-chlorophenyloxy)-4,5,6,7-tetrahydrofuro[3,2-c]pyridine | HCID 68412173 | — |
Reaction Steps
The same method as in Example 1 was conducted using 4,5,6,7-tetrahydrofuro[3,2-c]pyridin-7-ol (Reference Example 33) instead of 6-methyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-4-ol (Reference Example 6) and was conducted using 3-bromo-2-chloro-1-fluorobenzene instead of 1-fluoronaphthalene to give the objective compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217031B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-44cc1f0a424f4fe2b0e316f205331155 |
| Source note | uspto-grants-2012_07 |