HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3S)-(-)-3-(tert-Butoxycarbonylamino)pyrrolidine → (S)-1-(6-Methoxy-quinolin-4-yl)-pyrrolidin-3-ylamine
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3S)-(-)-3-(tert-Butoxycarbonylamino)pyrrolidine | HCID 1514396 | — |
| Edukt | 4-Bromo-6-methoxyquinoline | HCID 11160747 | — |
| Produkt | (S)-1-(6-Methoxy-quinolin-4-yl)-pyrrolidin-3-ylamine | HCID 66954035 | — |
Reaktionsschritte
Starting from (S)-pyrrolidin-3-yl-carbamic acid tert-butyl ester (commercial) and 4-bromo-6-methoxy-quinoline (commercial) the title compound was prepared according to procedure F followed by procedure E and was isolated as a brown oil (801 mg, 78% over two steps).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08217029B2 |
| Quelldatensatz | uspto-grants-2012_07 |
| ORD ID | ord-5fef4682c19e414c95ca18ccceb32b91 |
| Quellennotiz | uspto-grants-2012_07 |