Ethylamine → HCID 16727286, compound

HRID 1511825Notes

Reaction equation

HRID 1511825 reaction equation
[C:1]1([C:7]2[N:12]=[C:11]3[N:13]=[C:14]([NH:17][C:18](=[O:24])[C:19]([O:21]CC)=O)[CH:15]=[CH:16][C:10]3=[N:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:25]([NH2:27])[CH3:26]>C1COCC1>[CH2:25]([NH:27][C:19](=[O:21])[C:18]([NH:17][C:14]1[CH:15]=[CH:16][C:10]2[C:11]([N:13]=1)=[N:12][C:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)=[CH:8][N:9]=2)=[O:24])[CH3:26]

Participants

4

Reactant 2

HCID 6341EthylamineHCID 16727285HCID 16727285, compound

Product 1

HCID 16727286HCID 16727286, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

23 mg (0.07 mmol) of ethyl N-(3-phenylpyrido[2,3-b]pyrazin-6-yl)oxalamidate were dissolved in 5ml of dry THF and admixed with 0-15 ml (0.38 mmol) of a 2.0 M ethylamine solution in THF.

Sources & evidence

ORD record
ord-49b0c5fcf5b649c698e4f38c01f948fe
Source dataset
uspto-grants-2012_07
Patent number
US08217042B2

Reaction notes

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