Sodium Glycinate → HCID 54751137, compound

HRID 1511920Notes

Reaction equation

HRID 1511920 reaction equation
C(O[C:4]([C:6]1[C:11](=[O:12])[NH:10][N:9]2[CH:13]=[CH:14][CH:15]=[C:8]2[C:7]=1[OH:16])=[O:5])C.[NH2:17][CH2:18][C:19]([O-:21])=[O:20].[Na+]>COCCO>[OH:16][C:7]1[C:8]2[N:9]([CH:13]=[CH:14][CH:15]=2)[NH:10][C:11](=[O:12])[C:6]=1[C:4]([NH:17][CH2:18][C:19]([OH:21])=[O:20])=[O:5]

Participants

4

Reactant 2

HCID 4684308Sodium GlycinateHCID 67232111HCID 67232111, compound

Product 1

HCID 54751137HCID 54751137, compound

Reagents, catalysts & solvents 1

HCID 80192-MethoxyethanolSolvent

Procedure

Prepared according to the glycinolysis condition used in Example 1 step d) from 4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid ethyl ester (1.0 eq.) and sodium glycinate (15 eq.) in 2-methoxyethanol. ESI (m/z): 252 (M+H)+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b3a160943b9e4ffbbf9efc4ae8801eb4
Source dataset
uspto-grants-2012_07
Patent number
US08217043B2

Reaction notes

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