HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Chloro-4-(chloromethyl)benzene → (4-Chloro-benzyl)-pyrrol-1-yl-carbamic acid tert-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Chloro-4-(chloromethyl)benzene | HCID 7723 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | tert-Butyl 1H-pyrrol-1-ylcarbamate | HCID 49760548 | — |
| Product | (4-Chloro-benzyl)-pyrrol-1-yl-carbamic acid tert-butyl ester | HCID 67230228 | — |
Reaction Steps
Prepared according to the benzylation condition used in Example 1 step b) from pyrrol-1-yl-carbamic acid tert-butyl ester (1.0 eq.), 4-chlorobenzyl chloride (1.03 eq.) and sodium hydride (1.3 eq.). ESI (m/z): 307 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217043B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-8c743ffeb478420aae07b1db09bc24fe |
| Source note | uspto-grants-2012_07 |