Sodium Glycinate → HCID 54751145, compound

HRID 1511944Notes

Reaction equation

HRID 1511944 reaction equation
C(O[C:4]([C:6]1[C:11](=[O:12])[N:10]([CH2:13][C:14]2[CH:19]=[CH:18][C:17]([O:20][CH3:21])=[CH:16][CH:15]=2)[N:9]2[CH:22]=[CH:23][CH:24]=[C:8]2[C:7]=1[OH:25])=[O:5])C.[NH2:26][CH2:27][C:28]([O-:30])=[O:29].[Na+]>>[CH3:21][O:20][C:17]1[CH:16]=[CH:15][C:14]([CH2:13][N:10]2[C:11](=[O:12])[C:6]([C:4]([NH:26][CH2:27][C:28]([OH:30])=[O:29])=[O:5])=[C:7]([OH:25])[C:8]3=[CH:24][CH:23]=[CH:22][N:9]23)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 4684308Sodium GlycinateHCID 67230485HCID 67230485, compound

Product 1

HCID 54751145HCID 54751145, compound

Procedure

Prepared according to the glycinolysis condition used in Example 1 step d) from 1-(4-methoxy-benzyl)-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid ethyl ester (1.0 eq.) and sodium glycinate (15 eq.). ESI (m/z): 372 (M+H)+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-1678e5cad58842d69b62eabf084f77a2
Source dataset
uspto-grants-2012_07
Patent number
US08217043B2

Reaction notes

Loading…