Sodium Glycinate → HCID 54749293, compound

HRID 1511966Notes

Reaction equation

C(O[C:4]([C:6]1[C:11](=[O:12])[N:10]([CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18])[N:9]2[CH:19]=[CH:20][CH:21]=[C:8]2[C:7]=1[OH:22])=[O:5])C.[NH2:23][CH2:24][C:25]([O-:27])=[O:26].[Na+]>>[CH2:13]([N:10]1[C:11](=[O:12])[C:6]([C:4]([NH:23][CH2:24][C:25]([OH:27])=[O:26])=[O:5])=[C:7]([OH:22])[C:8]2=[CH:21][CH:20]=[CH:19][N:9]12)[CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

Reactant 2

HCID 4684308Sodium Glycinate

HCID 67230194HCID 67230194, compound

Product 1

HCID 54749293HCID 54749293, compound

Procedure

Prepared according to the glycinolysis condition used in Example 1 step d) from 1-hexyl-4-hydroxy-2-oxo-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid ethyl ester (1.0 eq.) and sodium glycinate (15 eq.). ESI (m/z): 336 (M+H)+.

Workup

customPrepared

Sources & evidence

ORD record: ord-8783e21f979449f9b28067bd6a8c397c
Source dataset: uspto-grants-2012_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08217043B2

Reaction notes

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