HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → HCID 67231385, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | ethyl 5-fluoro-1H-indole-2-carboxylate | HCID 2727899 | — |
| Reactant | Sodium Hypochlorite | HCID 23665760 | — |
| Catalyst | Trioctylmethylammonium chloride | HCID 21218 | — |
| Product | HCID 67231385 | HCID 67231385 | — |
Reaction Steps
Prepared according to the N-amination condition used in Example 18 step a) from 5-fluoro-1H-indole-2-carboxylic acid ethyl ester (prepared according to literature: J. Chem. Soc. 1955, 1283-1284), ammonium chloride, ALIQUAT 336, sodium hydroxide, concentrated ammonium hydroxide solution and 10% solution of NaOCl. ESI (m/z): 223 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217043B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-1b7c05d529174d038c961f59b0b70d0f |
| Source note | uspto-grants-2012_07 |