Methyl malonyl chloride → HCID 67231001, compound

Participants

Reaction Steps

Prepared according to the acylation condition used in Example 2 step f) from 5-fluoro-1-(4-fluoro-benzylamino)-1H-indole-2-carboxylic acid ethyl ester and chlorocarbonyl-acetic acid methyl ester (1.2 eq.). 1H NMR (CDCl3, δ in ppm): 7.3-6.77 (m, 8H), 4.82 (dd, 2H), 4.17 (m, 2H), 3.54 (s, 3H), 3.26 (s, 2H), 1.31 (t, 3H, J=7.1 Hz).

Provenance & Evidence