Sodium Glycinate → HCID 54746445, compound

HRID 1511981Notes

Reaction equation

HRID 1511981 reaction equation
CO[C:3]([C:5]1[C:10](=[O:11])[N:9]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)[N:8]2[CH:20]=[C:21]([Cl:23])[CH:22]=[C:7]2[C:6]=1[OH:24])=[O:4].[NH2:25][CH2:26][C:27]([O-:29])=[O:28].[Na+]>>[Cl:23][C:21]1[CH:22]=[C:7]2[C:6]([OH:24])=[C:5]([C:3]([NH:25][CH2:26][C:27]([OH:29])=[O:28])=[O:4])[C:10](=[O:11])[N:9]([CH2:12][C:13]3[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=3)[N:8]2[CH:20]=1

Participants

3

Reactant 2

HCID 4684308Sodium GlycinateHCID 67230724HCID 67230724, compound

Product 1

HCID 54746445HCID 54746445, compound

Procedure

Prepared according to the glycinolysis condition used in Example 1 step d) from 6-chloro-4-hydroxy-2-oxo-1-(4-chloro-benzyl)-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid methyl ester (1.0 eq.) and sodium glycinate (15 eq.). ESI (m/z): 410 (M+H)+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-08c97762528c42d6be4826743d2af55d
Source dataset
uspto-grants-2012_07
Patent number
US08217043B2

Reaction notes

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