Sodium Glycinate → HCID 54751161, compound

HRID 1511985Notes

Reaction equation

HRID 1511985 reaction equation
CO[C:3]([C:5]1[C:10](=[O:11])[N:9]([CH2:12][C:13]2[CH:18]=[CH:17][C:16]([O:19][CH3:20])=[CH:15][CH:14]=2)[N:8]2[CH:21]=[C:22]([Cl:24])[CH:23]=[C:7]2[C:6]=1[OH:25])=[O:4].[NH2:26][CH2:27][C:28]([O-:30])=[O:29].[Na+]>>[Cl:24][C:22]1[CH:23]=[C:7]2[C:6]([OH:25])=[C:5]([C:3]([NH:26][CH2:27][C:28]([OH:30])=[O:29])=[O:4])[C:10](=[O:11])[N:9]([CH2:12][C:13]3[CH:14]=[CH:15][C:16]([O:19][CH3:20])=[CH:17][CH:18]=3)[N:8]2[CH:21]=1

Participants

3

Reactant 2

HCID 4684308Sodium GlycinateHCID 67229790HCID 67229790, compound

Product 1

HCID 54751161HCID 54751161, compound

Procedure

Prepared according to the glycinolysis condition used in Example 1 step d) from 6-chloro-4-hydroxy-2-oxo-1-(4-methoxy-benzyl)-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid methyl ester (1.0 eq.) and sodium glycinate (15 eq.). ESI (m/z): 406 (M+H)+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-da1394be779541dd95325cf4f0b06469
Source dataset
uspto-grants-2012_07
Patent number
US08217043B2

Reaction notes

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