Sodium Glycinate → HCID 54751170, compound

HRID 1512001Notes

Reaction equation

HRID 1512001 reaction equation
CO[C:3]([C:5]1[C:10](=[O:11])[N:9]([CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=2)[N:8]2[CH:19]=[C:20]([Cl:22])[CH:21]=[C:7]2[C:6]=1[OH:23])=[O:4].[NH2:24][CH2:25][C:26]([O-:28])=[O:27].[Na+]>>[Cl:22][C:20]1[CH:21]=[C:7]2[C:6]([OH:23])=[C:5]([C:3]([NH:24][CH2:25][C:26]([OH:28])=[O:27])=[O:4])[C:10](=[O:11])[N:9]([CH2:12][C:13]3[CH:18]=[CH:17][CH:16]=[CH:15][N:14]=3)[N:8]2[CH:19]=1

Participants

3

Reactant 2

HCID 4684308Sodium GlycinateHCID 67230037HCID 67230037, compound

Product 1

HCID 54751170HCID 54751170, compound

Procedure

Prepared according to the glycinolysis condition used in Example 1 step d) from 6-chloro-4-hydroxy-2-oxo-1-pyridin-2-ylmethyl-1,2-dihydro-pyrrolo[1,2-b]pyridazine-3-carboxylic acid methyl ester (1.0 eq.) and sodium glycinate (5 eq.). ESI (m/z): 377 (M+H)+.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-6bd8d9d2de2843fcb1ec016fd046b458
Source dataset
uspto-grants-2012_07
Patent number
US08217043B2

Reaction notes

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