Methyl malonyl chloride → HCID 67230931, compound

Participants

Reaction Steps

Prepared according to the acylation condition used in Example 2 step f) from 4,5-dichloro-1-(4-fluoro-benzylamino)-1H-pyrrole-2-carboxylic acid methyl ester and chlorocarbonyl-acetic acid methyl ester (1.5 eq.). 1H NMR (CDCl3, δ in ppm): 7.1-6.8 (m, 5H), 4.88 (d, 1H, J=14.6 Hz), 4.75 (d, 1H, J=14.0 Hz), 3.72 (s, 3H), 3.67 (s, 3H), 3.17 (dd, 2H).

Provenance & Evidence