反应详情

A solution of 2-(2-cyclohexyl-vinyl)-5-(2-trifluoromethoxy-phenyl)-1H-benzimidazole (0.3 g, 0.78 mmol, prepared as in STEP C above) in ethyl ether (5 mL) was treated with 2M HCl in ethyl ether (0.8 mmol, 0.4 mL). After five minutes the resulting solution was concentrated and dried in vacuo to yield the title compound.

1. concentrationAfter five minutes the resulting solution was concentrated
2. customdried in vacuo