反应详情

Following the procedure as described in Example 3, STEP B, the title compound was prepared from 4-bromo-2-nitro-phenylamine (2.06 g, 9.47 mmol) and (E)-3-(tetrahydro-pyran-4-yl)-acrylic acid (prepared as described in PCT Publication WO 2005/101989 (A2,A3), 1.14 g, 7.29 mmol) and was obtained as a yellow solid.

1. customwas obtained as a yellow solid