HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-nitroaniline → (E)-N-(4-Bromo-2-nitro-phenyl)-3-(tetrahydro-pyran-4-yl)-acrylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-nitroaniline | HCID 70132 | — |
| Reactant | HCID 17786652 | HCID 17786652 | — |
| Product | (E)-N-(4-Bromo-2-nitro-phenyl)-3-(tetrahydro-pyran-4-yl)-acrylamide | HCID 67528902 | — |
Reaction Steps
Following the procedure as described in Example 3, STEP B, the title compound was prepared from 4-bromo-2-nitro-phenylamine (2.06 g, 9.47 mmol) and (E)-3-(tetrahydro-pyran-4-yl)-acrylic acid (prepared as described in PCT Publication WO 2005/101989 (A2,A3), 1.14 g, 7.29 mmol) and was obtained as a yellow solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217060B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-fad9cab1ccca4465ae610a2db0dd98df |
| Source note | uspto-grants-2012_07 |