HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Nitro-2'-trifluoromethyl-biphenyl-4-ylamine → (E)-2-[2-(4-Methyl-tetrahydro-pyran-4-yl)-vinyl]-5-(2-trifluoromethyl-phenyl)-1H-benzimidazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Nitro-2'-trifluoromethyl-biphenyl-4-ylamine | HCID 50994036 | — |
| Reactant | HCID 67528472 | HCID 67528472 | — |
| Product | (E)-2-[2-(4-Methyl-tetrahydro-pyran-4-yl)-vinyl]-5-(2-trifluoromethyl-phenyl)-1H-benzimidazole | HCID 178422995 | — |
Reaction Steps
(E)-2-[2-(4-Methyl-tetrahydro-pyran-4-yl)-vinyl]-5-(2-trifluoromethyl-phenyl)-1H-benzimidazole was prepared from the acid chloride of 3-(4-methyl-tetrahydro-pyran-4-yl)-acrylic acid (prepared as in STEP B above) and 3-nitro-2′-trifluoromethyl-biphenyl-4-ylamine (prepared as described in Example 3, STEP A) following the procedure as described in Example 8, STEP C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217060B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-13fff5b1129d4b9c8a8ac71a4e6bc568 |
| Source note | uspto-grants-2012_07 |