2,2,2-Trifluoroethanol → HCID 63669049, compound

HRID 1512261Notes

Reaction equation

HRID 1512261 reaction equation
F[C:2]1[CH:9]=[CH:8][C:7]([F:10])=[CH:6][C:3]=1[C:4]#[N:5].[F:11][C:12]([F:16])([F:15])[CH2:13][OH:14]>>[F:10][C:7]1[CH:8]=[CH:9][C:2]([O:14][CH2:13][C:12]([F:16])([F:15])[F:11])=[C:3]([CH:6]=1)[C:4]#[N:5]

Participants

3

Reactant 2

HCID 64092,2,2-TrifluoroethanolHCID 1235582,5-Difluorobenzonitrile

Product 1

HCID 63669049HCID 63669049, compound

Procedure

2,5-difluoro-benzonitrile was reacted with 2,2,2-trifluoro-ethanol according to the method of Example 84A to provide the title compound. MS (DCI/NH3) m/z 220 (M+1)+.

Sources & evidence

ORD record
ord-2b2b86ed086842cd818928af3d271c67
Source dataset
uspto-grants-2012_07
Patent number
US08217067B2

Reaction notes

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