HuagongsheHuagongshe Chemistry Print Report · For research reference only
Azetidine hydrochloride → HCID 68583271, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Azetidine hydrochloride | HCID 12308726 | — |
| Reactant | 2-Chloro-5-fluoropyridine-3-carbonitrile | HCID 23110851 | — |
| Product | HCID 68583271 | HCID 68583271 | 78% |
Reaction Steps
Prepared in 78% yield from the product of Example 169A and azetidine hydrochloride according to the procedure described for Example 178A. MS (ESI+) m/z 177.8 (M+H)+; 1H NMR (DMSO-d6) δ 2.28-2.38 (m, 2H), 4.17-4.22 (m, 4H), 8.07 (dd, J=8.3, 2.9 Hz, 1H), 8.66 (dd, J=8.1, 3.0 Hz, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08217067B2 |
| Source dataset | uspto-grants-2012_07 |
| ORD ID | ord-7a5ef52d9f254bf095acaa2d9eb1a2d9 |
| Source note | uspto-grants-2012_07 |