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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1512342Generated: November 2, 2026

Pyrrolidine → HCID 68582180, compound

https://huagongshe.com/reaction/1512342

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPyrrolidineHCID 31268—
Reactant2,5,6-TrifluoronicotinonitrileHCID 40427165—
ProductHCID 68582180HCID 6858218057%

Reaction Steps

Prepared in 57% yield from 2,5,6-Trifluoro-nicotinonitrile and pyrrolidine according to the procedure described for Example 178A. 1H NMR (DMSO-d6) δ 1.85-1.93 (m, 4H), 3.55-3.62 (m, 4H), 8.01 (dd, J=12.2, 6.8 Hz, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08217067B2
Source datasetuspto-grants-2012_07
ORD IDord-c404ab77effb4f799d647e2deeebc943
Source noteuspto-grants-2012_07