Nitric Acid → HCID 178433493, compound

Participants

Reaction Steps

To fuming nitric acid (50 mL) was added 4,6-dihydroxy-2-methylpyrimidine (25 g) slowly under ice-cooling, and the mixture was stirred at the same temperature for 15 minutes. To the reaction mixture was added ice water (500 mL), and the resulting mixture was stirred at room temperature until the ice melted. The precipitated crystals were collected by filtration. The collected crystals were washed with water, and dried under reduced pressure to give the title compound (26.6 g).

Provenance & Evidence