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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1513344Generated: November 3, 2026

Hydrochloric Acid → HCID 68433547, compound

https://huagongshe.com/reaction/1513344

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 25222719HCID 25222719—
SolventDiethyl EtherHCID 3283—
ProductHCID 68433547HCID 68433547—

Reaction Steps

6-methyl-2-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-1,2,4-triazine-3,5(2H,4H)-dione was dissolved in Et2O and treated with HCl 1N in Et2O to form the title compound 6-methyl-2-(3-{(1S,5R)-1-[4-(trifluoromethyl)phenyl]-3-azabicyclo[3.1.0]hex-3-yl}propyl)-1,2,4-triazine-3,5(2H,4H)-dione hydrochloride salt (E2, 73.8 mg, 0.171 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08217168B2
Source datasetuspto-grants-2012_07
ORD IDord-ba943f30762c412086ce25e3523a34dd
Source noteuspto-grants-2012_07