Dimethylformamide → HCID 74949036, compound
Reaction equation
[C:1]([OH:12])(=O)[CH:2]=[CH:3][CH2:4][CH2:5][CH:6]=[CH:7][CH:8]=[CH:9][CH3:10].CN(C=O)C.S(Cl)([Cl:20])=O>C1(C)C=CC=CC=1>[C:1]([Cl:20])(=[O:12])[CH:2]=[CH:3][CH2:4][CH2:5][CH:6]=[CH:7][CH:8]=[CH:9][CH3:10]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 5 °C
Procedure
In an atmosphere of nitrogen, a toluene solution of the above-mentioned 2,6,8-decatrienoic acid (7) and DMF (3.7 g, 0.05 mol) were added to a 100 ml capacity flask, followed by cooling to 5° C. Thionyl chloride (11.9 g, 0.10 mol) was added dropwise to this, followed by stirring at 5° C. for 0.5 hour to obtain a toluene solution of 2,6,8-decatrienoic acid chloride (8).
Sources & evidence
- ORD record
- ord-13750b2ac8ae47199d50fe5ee39b40ce
- Source dataset
- uspto-grants-2012_07
- Patent number
- US08217192B2
Reaction notes
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