反应详情

A mixture of 2 (2.89 g, 9.4 mmol), 3,4-dihydro-2H-pyran (1.19 g, 14.1 mmol), pyridine p-toluenesulfonate (0.236 g, 0.94 mmol) and CH2Cl2 (50 ml) was stirred overnight at r.t. The solvent was evaporated and the product purified on silica gel (petroleum ether, by 40-60° C./ethyl acetate 2:5), yielding 3.18 g (86%) of the title compound.

1. customThe solvent was evaporated
2. customthe product purified on silica gel (petroleum ether, by 40-60° C./ethyl acetate 2:5)