Water → HCID 131729817, compound

HRID 1514000Notes

Reaction equation

HRID 1514000 reaction equation
[Eu+3:1].[C:2]([C:5]1[C:6]([CH3:75])=[C:7]([C:11]2[CH:16]=[C:15]([C:17]([OH:19])=[O:18])[N:14]=[C:13]([CH2:20][N:21]3[CH2:29][CH2:28][N:27]([CH2:30][C:31]4[CH:36]=[C:35]([C:37]5[O:38][C:39]([CH3:46])=[C:40]([C:43]([OH:45])=[O:44])[C:41]=5[CH3:42])[CH:34]=[C:33]([C:47]([OH:49])=[O:48])[N:32]=4)[CH2:26][CH2:25][N:24]([CH2:50][C:51]4([C:72]([OH:74])=[O:73])[CH:56]=[C:55]([C:57]5[O:58][C:59]([CH3:71])=[C:60]([C:63]([NH:65][CH2:66][CH2:67][CH2:68][CH2:69][NH2:70])=[O:64])[C:61]=5[CH3:62])[CH:54]=[CH:53][NH:52]4)[CH2:23][CH2:22]3)[CH:12]=2)[O:8][C:9]=1[CH3:10])([OH:4])=[O:3].[N:76]1[C:83]([Cl:84])=[N:82][C:80](Cl)=[N:79][C:77]=1[Cl:78].O.[OH-].[Na+]>CC(O[Na])=O.CC(C)=O>[Eu+3:1].[C:2]([C:5]1[C:6]([CH3:75])=[C:7]([C:11]2[CH:16]=[C:15]([C:17]([OH:19])=[O:18])[N:14]=[C:13]([CH2:20][N:21]3[CH2:29][CH2:28][N:27]([CH2:30][C:31]4[CH:36]=[C:35]([C:37]5[O:38][C:39]([CH3:46])=[C:40]([C:43]([OH:45])=[O:44])[C:41]=5[CH3:42])[CH:34]=[C:33]([C:47]([OH:49])=[O:48])[N:32]=4)[CH2:26][CH2:25][N:24]([CH2:50][C:51]4([C:72]([OH:74])=[O:73])[CH:56]=[C:55]([C:57]5[O:58][C:59]([CH3:71])=[C:60]([C:63]([NH:65][CH2:66][CH2:67][CH2:68][CH2:69][NH:70][C:80]6[N:82]=[C:83]([Cl:84])[N:76]=[C:77]([Cl:78])[N:79]=6)=[O:64])[C:61]=5[CH3:62])[CH:54]=[CH:53][NH:52]4)[CH2:23][CH2:22]3)[CH:12]=2)[O:8][C:9]=1[CH3:10])([OH:4])=[O:3]

Participants

7

Reactant 4

HCID 962WaterHCID 7954Cyanuric chlorideHCID 14798Sodium HydroxideHCID 131729818HCID 131729818, compound

Product 1

HCID 131729817HCID 131729817, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 178418247HCID 178418247, compoundSolvent

Procedure

Compound 23 (4.5 mg, 3.9 μmol) was dissolved in 1 mL of 0.1M CH3COONa (pH 6.5). Cyanuric chloride (0.8 mg, 4.2 mmol) was dissolved in acetone (1 mL) and 0.3 mL water was added. The solutions were combined, the pH was adjusted to 6.5 with 0.1 M NaOH-solution and the mixture was stirred for 20 min at r.t. The product was precipitated by adjusting the pH to 3 with 1 M HCl. The precipitate was washed twice with 2 mL of acetone and dried in a vacuum desiccator.

Workup

  1. customThe product was precipitated
  2. washThe precipitate was washed twice with 2 mL of acetone
  3. customdried in a vacuum desiccator

Sources & evidence

ORD record
ord-d4ff3a5e45b4408d9bcc992485434558
Source dataset
uspto-grants-2012_07
Patent number
US08221719B2

Reaction notes

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